Last updated February 13, 2023
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TIGRFAMs is a resource consisting of curated multiple sequence alignments, Hidden Markov Models (HMMs) for protein sequence classification, and associated information designed to support automated annotation of (mostly prokaryotic) proteins. Starting with release 10.0, TIGRFAMs models use HMMER3, which provides excellent search speed as well as exquisite search sensitivity.

Use the widget below to access the data in this database. Use the filter in the top right corner to narrow down the results. Once you have found the item you need, simply select it and the directory path will be copied to your clipboard. Paste the path in your submission scripts to use in your analysis. If you would like to see the path displayed in the widget, select the Detailed View option.