Last updated February 13, 2023
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The Universal Protein Resource (UniProt), a collaboration between the European Bioinformatics Institute (EBI), the SIB Swiss Institute of Bioinformatics, and the Protein Information Resource (PIR), is comprised of three databases, each optimized for different uses. The UniProt Knowledgebase (UniProtKB) is the central access point for extensively curated protein information, including function, classification and cross-references. The UniProt Reference Clusters (UniRef) combine closely related sequences into a single record to speed up sequence similarity searches. The UniProt Archive (UniParc) is a comprehensive repository of all protein sequences, consisting only of unique identifiers and sequences.

The UniProt Knowledgebase (UniProtKB) has been created from Swiss-Prot, TrEMBL and PIR-PSD. It consists of two parts, one containing fully manually annotated records and another one with computationally analyzed records awaiting full manual annotation. The two sections will be referred to as the Swiss-Prot section of the UniProt Knowledgebase (UniProtKB/Swiss-Prot) and TrEMBL section of the UniProt Knowledgebase (UniProtKB/TrEMBL), respectively. PIR-PSD release 80.0 of 31-Dec-2004 has been fully integrated into these sections. This was the last release of PIR-PSD.

Use the widget below to access the data in this database. Use the filter in the top right corner to narrow down the results. Once you have found the item you need, simply select it and the directory path will be copied to your clipboard. Paste the path in your submission scripts to use in your analysis. If you would like to see the path displayed in the widget, select the Detailed View option.